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Site Rotation : Rotate injection sites systematically to prevent lipodystrophy and maintain consistent absorption
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Rucaparib was the second PARP inhibitor approved, receiving FDA accelerated approval in 2016 based on the findings of the ARIEL2 trial for patients with BRCA-mutated, relapsed ovarian cancer and, subsequently, approval as a maintenance therapy for patients with platinum-sensitive ovarian cancer based on the results of the ARIEL3 trial in 2018 [163]
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