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Salt is a major component in protein purification buffers, and optimizing this important parameter can make or break a purification step
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In the nucleus, following heterodimer complex formation with transcription factors, like small Maf proteins (G/F/K) and c-Jun, Nrf2 complexes bind to the antioxidant response element (ARE), a regulatory enhancer region within gene promoters that upregulate antioxidant and anti-inflammatory defense processes (McCord et al., 2020
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